Comparative Metabolism of Certain Aromatic Acids. Ix. Fate of Some Halogen Derivatives of Benzoic Acid in the Aninal Body
نویسنده
چکیده
In the literature one finds comparatively few references to the fate of the benaoic acid derivatives in the animal body, and even some rather conflicting statements regarding several of the corresponding hippuric acids. The object of our work, therefore, was to prepare the o-, m-, and p-chloro-, bromo-, and iodobenzoic acids, and, by feeding these substances to dogs and rabbits, to compare the products isolated from the urine with the corresponding hippuric acids synthesized in the laboratory.
منابع مشابه
The origin of urinary aromatic compounds excreted by ruminants. 2. The metabolism of phenolic cinnamic acids to benzoic acid.
1. The extent to which phenolic derivatives of benzoic acid (seven); of phenylacetic acid (one); of 3-phenylpropionic acid (one) and of cinnamic acid (six) served as precursors of the urinary benzoic acid excreted by sheep was determined after administration as continuous drips via rumen or abomasal cannulas. 2. Phenolic derivatives of benzoic or of phenylacetic acid were not dehydroxylated to ...
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